The
Beecher Tissue
Microarrayer generates multiple specimen slides that can
contain hundreds of individual tissues. An array is constructed
by inserting 0.6-2.0 mm plugs removed from original tissue
blocks into a fresh paraffin block. The plugs are so small
that sampling does not damage the original tissue blocks,
yet the spots are large enough to provide a representative
view of the tissue morphology.
Instead
of incubating and analyzing samples one slide at a time,
tissue microarrays permit the simultaneous examination
of more than a hundred samples on just one slide. All
the histochemical and molecular detection techniques that
can be used with regular sections can also be used with
tissue microarrays.